Don’t panic, but there is another virus out there that could cause a pandemic.  This one is an influenza strain circulating in pigs and their caretakers in China.  It is not currently causing widespread illness, and it may never do so. But it has “all the essential hallmarks of a candidate pandemic virus,” according to the authors of a new study in the FILE – A patient receives a flu vaccination in Mesquite, Texas, January 23, 2020.‘Good news, bad news’ “There’s good news and bad here,” Pavia said. “I think the bad news is that once again, it looks as if we’re identifying strains of flu that are emerging in populations with the potential to jump to humans.”However, only a handful of serious cases have been reported.”The severity remains low. That’s good news,” Pavia said, adding, “there’s no guarantee that it’s going to stay that way.”Other factors also must change before alarm bells really go off, experts note.”What is really important for influenza pandemic emergence, as well as for any viral pandemic emergence, is sustained airborne transmission,” said University of Pittsburgh School of Medicine microbiologist and molecular geneticist Seema Lakdawala, who was not part of the research team.While a few people are getting infected, she said there is no sign now of sustained transmission.Food animals are a common source of new flu viruses. Birds, pigs and humans can all exchange flu strains. Pigs are especially welcoming environments for influenza viruses to reinvent themselves. Multiple strains can infect one animal, swap genes and emerge as a novel strain.Unpredictable There is no telling when the right combination of genes will fall into place and produce a virulent, transmissible virus.A lethal strain called H5N1 first appeared in poultry in Hong Kong in 1997 and resurfaced in 2003. It kills more than half the people it infects. But for reasons scientists do not understand, it has not gone pandemic.”It’s still a concern. It has caused hundreds of deaths,” said senior scholar Gigi Gronvall at the Johns Hopkins Center for Health Security, who was not involved with the research. “But for whatever reason, even though all eyes were on that, it was this other virus that took off in 2009.” FILE – Researchers of the Veterinary Institute under the Academy of Agricultural Research check on African Swine Flu at Ryongsong District in Pyongyang, North Korea, June 10, 2019.That year, H1N1 emerged from pigs and sparked a pandemic. Researchers estimate that nearly 300,000 people died from it in the first year. Since then, health officials have increased efforts to monitor livestock farms and markets for new viruses.”There’s been a big improvement, but it’s far from complete,” Pavia said. “The challenge is enormous. Influenza circulates among ducks, turkeys, swine – not to mention there are strains that infect everything from horses to dogs. And tracking all of these is an enormous task.”The effort is understaffed and underfunded, “like so many things in public health,” he said.And that’s dangerous. “We’ve seen the consequences of inadequate public health surveillance in the emergence and failure to control COVID-19,” Pavia noted. Flu tools Unlike COVID-19, health experts have tools against influenza that might help if the new strain were to launch a new pandemic.  “We know how to test for influenza viruses,” Lakdawala said. Flu antivirals are only partly effective, “but we do at least have antivirals that can limit the severity of disease. We have a number of them. We also have a vaccine platform that is already approved and safe.”  A vaccine could be available in a matter of months.  But there is no way to know whether the newly identified strain will spark a pandemic.”The more you study flu, the more you realize we just don’t know how to predict that,” Pavia said.  
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A new study published this week in the Journal of Neuroscience suggests weightlifting affects a person’s brain weeks before there is a noticeable change in muscles. The study, conducted by researchers at New Castle University in northeast Britain, used macaque monkeys, whose brain systems are similar to humans in regard to movement.   The researchers trained the monkeys to pull a weighted handle with one arm by rewarding them with food. Over the course of three months, researchers increased the resistance of a weighted handle week by week. The monkeys completed daily strength training sessions, including 50 weighted pulls (moving the handle at least 4 centimeters). FILE – Russia’s Andrey Demanov competes during the men’s 94kg group A weightlifting event of the London 2012 Olympic Games at The Excel Centre in London on August 4, 2012.The experiment revealed that weightlifting strengthens the nervous system through a motor tract called the reticulospinal tract, and this change occurs weeks before any muscle is added. Newcastle University researcher Isabel Glover, co-author of the study, explained that when people lift weights, they get stronger because the neural input to the muscles increases.  “It’s a few weeks later that the muscles themselves start to get bigger,” Glover said. Professor Stuart Baker, the study’s other co-author, said this change in the nervous system helps weightlifters activate their existing muscles more efficiently. Baker said these neural changes in the brain also have other physiological benefits. “If we understand the neural mechanisms of strength, then we can start to think about how to help individuals suffering from a loss of strength, such as following a stroke,” he said.  
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Something data crunchers have noticed during the coronavirus pandemic: countries with recent outbreaks of measles have fewer deaths and serious illnesses from the coronavirus. Is this a coincidence? Or is there something about the measles mumps and rubella vaccine that protects against the worst outcomes of the coronavirus? We learn more from VOA’s Carol Pearson.Produced by: Barry Unger
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Scientists in China have identified a new strain of a flu virus in pigs that has the potential to infect humans and lead to a new pandemic.
 
In a paper published in the U.S.-based journal Proceedings of the National Academy of Sciences, the scientists say the new “G4” strain was discovered during a surveillance program of pig farms and slaughterhouses across 10 provinces between 2011 and 2018.   
 
The new virus is a variation of the H1N1 swine flu virus that killed hundreds of thousands of people around the world in 2009.   
 
The scientists discovered the G4 virus has already infected workers at various farms and slaughterhouses throughout China.  The new H1N1 strain can grow and quickly multiply in the cells that line the airways of humans, although there is no current evidence the illness can spread through human-to-human contact.   
 
But the researchers also found that although G4 is derived from H1N1, current flu vaccines do not provide any immunity from the new virus.
 
The research paper said that G4 have all the “essential hallmarks of a candidate pandemic virus.”  The scientists urged pig farmers to control the spread of the virus among pigs, and to closely monitor people who work with the animals.   
 
The study’s release comes as the world is in the grips of COVID-19 pandemic which has sickened over 10.2 million people worldwide and killed over 500,000 since it was first detected late last year in the central city of Wuhan.   
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Researchers in China have discovered a new type of swine flu that is capable of triggering a pandemic, according to a study published Monday in the U.S. science journal PNAS. Named G4, it is genetically descended from the H1N1 strain that caused a pandemic in 2009. It possesses “all the essential hallmarks of being highly adapted to infect humans,” say the authors, scientists at Chinese universities and China’s Center for Disease Control and Prevention.  From 2011 to 2018, researchers took 30,000 nasal swabs from pigs in slaughterhouses in 10 Chinese provinces and in a veterinary hospital, allowing them to isolate 179 swine flu viruses.   The majority were of a new kind, which has been dominant among pigs since 2016. The researchers then carried out various experiments including on ferrets, which are widely used in flu studies because they experience similar symptoms to humans, principally fever, coughing and sneezing.   G4 was observed to be highly infectious, replicating in human cells and causing more serious symptoms in ferrets than other viruses. Tests also showed that any immunity humans gain from exposure to seasonal flu does not provide protection from G4. According to blood tests, which showed antibodies created by exposure to the virus, 10.4% of swine workers had already been infected. The tests showed that as many as 4.4% of the general population also appeared to have been exposed.  The virus has therefore already passed from animals to humans but there is no evidence yet that it can be passed from human to human, the scientists’ main worry. “It is of concern that human infection of G4 virus will further human adaptation and increase the risk of a human pandemic,” the researchers wrote. The authors called for urgent measures to monitor people working with pigs.  “The work comes as a salutary reminder that we are constantly at risk of new emergence of zoonotic pathogens and that farmed animals, with which humans have greater contact than with wildlife, may act as the source for important pandemic viruses,” said James Wood, head of the department of veterinary medicine at Cambridge University. A zoonotic infection is caused by a pathogen that has jumped from a non-human animal into a human. 
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The Trump administration says it has locked down nearly the entire supply of one of the only available anti-COVID-19 drugs from the manufacturer for the next several months. That raises questions about access to one of the few treatments available for COVID-19, the disease caused by the coronavirus, for much of the rest of the world. Remdesivir is the first drug shown to help patients with COVID-19, though its impact is modest. Hospitalized patients given the drug recovered four days faster than those given a placebo. FILE – Vials of the drug remdesivir are seen at a hospital in Germany, April 8, 2020.FILE – Gilead Sciences pharmaceutical company is seen during the outbreak of the coronavirus disease (COVID-19), in La Verne, California.The Institute for Clinical and Economic Review, the drug pricing watchdog, said Gilead’s price is “reasonable,” provided the drug ultimately shows it can save lives.Gilead donated the first 1.5 million doses worldwide. The United States received more than 900,000, according to health news website Stat. “The U.S. was certainly at the front of the line for the donated remdesivir,” said Brook Baker, professor of law at Northeastern University and a senior policy analyst for Health Global Access Project. “Now, we find out that the U.S. is wholly at the front of the line for all the additional half-million doses to be produced between now and basically the end of September.” “There’s no way to explain this than to say, well, somehow between the U.S. government and Gilead, they have collusively agreed that for whatever reason, Americans come first,” he added. Gilead says it is ramping up production and aims to have 2 million treatment courses available by December, up from 190,000 at the end of June.   “We are doing everything we can to accelerate manufacturing timelines and quantities of remdesivir to meet the growing demand for emergency use of the medicine from around the world,” the company said in a statement. The company said it has “multiple manufacturing partners in North America, Europe and Asia” that are “capable of producing large volumes of remdesivir at the fastest pace feasible,” but did not provide details or answer requests for comment.The global pandemic so far has claimed more than 500,000 lives and infected more than 10 million people worldwide, according to data collected by Johns Hopkins University.  The World Health Organization and a number of public-private partnerships are aiming to make access to COVID-19 countermeasures equitable around the world.The U.S. government has put billions of dollars into research and development of COVID-19 treatments, vaccines and diagnostics.  “Rich countries have more money to spend on research and development,” Baker said. “Does that mean that only rich people get medicine? That’s highly problematic in a moral, ethical sense.”  
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Wanda Johnson’s son was shot and killed by a police officer in Oakland, California, 11 years ago, she has watched video after video of similar encounters between Black people and police.  Each time, she finds herself reliving the trauma of losing her son, Oscar Grant, who was shot to death by a transit police officer. Most recently, Johnson couldn’t escape the video of George Floyd, pinned to the ground under a Minneapolis officer’s knee as he pleaded that he couldn’t breathe.  “I began to shake. I was up for two days, just crying,” she said. “Just looking at that video opened such a wound in me that has not completely closed.”  Johnson’s loss was extreme, but, for many Black Americans, her grief and pain feels familiar. Psychologists call it racial trauma — the distress experienced because of the accumulation of racial discrimination, racial violence or institutional racism. While it can affect anyone who faces repeated prejudice, in this moment, its impact on Black people is drawing particular attention.  The unfortunate irony is that the very tool that may be helping to make more people aware of the racism and violence that Black and other people of color face is also helping to fuel their trauma. In the weeks following Floyd’s death, the spread of the video that captured it has been a major catalyst for protests demanding a reckoning with racism — attended by people of all races, many of whom never before participated in such activism. And in a few weeks, the national conversation has shifted dramatically: The term “Black Lives Matter” has been adopted widely, including in corporate America, monuments of Confederate figures have come down, and calls for criminal justice reform have yielded new laws.  “It’s really frustrating that that’s what it takes for a lot of people in this country to actually start caring,” said Alasia Destine-DeFreece, 20. “It takes showing something that’s  actively harming those of us who are Black and then having it spread on social media.”  Destine-DeFreece, who remembers often being the only Black person in many situations growing up in Rhode Island, notes that such images have been used to great effect before. She learned in school about Emmett Till, a Black 14-year-old who was abducted, beaten and killed in 1955 after he was accused of whistling at a white woman in Mississippi. Her class saw photos of Till’s brutally beaten face — images, in part, that had helped spur the civil rights movement. “Seeing that type of imagery being spread further and faster now has taken a toll on me. You’re seeing somebody who looks like you die,” she said. Symptoms of racial trauma can include anxiety and depression and be similar to those of post-traumatic stress disorder. The triggering event could be a shouted slur on the street or poor treatment because of one’s race or creed. The profusion on social media of graphic images of harm to people of color means they are often inescapable. “If you are in a situation where the danger seems ever-present, whether you’re seeing a bird watcher in Central Park being harassed, or someone falling asleep in their car in a parking lot … there is that constant physical presence of danger and the psychological awareness that danger is just around the corner,” said Dr. Altha Stewart, past president of the American Psychiatric Association and currently a senior associate dean at the University of Tennessee Science Health Center. That “constant bathing of our organs” in stress hormones can lead to a state of “near dysfunction,” she said. The video of Floyd’s killing is one in a litany. Before it, 25-year-old Ahmaud Arbery’s fatal shooting was also captured on camera, and no one was charged until public pressure mounted after the video made the rounds. Since then, many have watched an officer fatally shoot 27-year-old Rayshard Brooks in the back following a struggle.  “It feels like it’s just been an endless cascade of hashtags of Black people dying,” said Christine Ohenzuwa, 19, who recently protested outside the Minnesota state Capitol. “I feel like for me and a lot of other Black people, it reaches a point where it’s just very traumatic to constantly see Black people being killed.” When video of Floyd’s graphic death began to circulate online last month, Joi Lewis refused to watch it. “I know what it looks like. I’ve seen Black death,” the life coach and self-care expert said. Lewis, who is Black, had watched the death of Philando Castile in real time four years ago, after the 32-year-old Black man was shot by a Minneapolis police officer and video of the immediate aftermath streamed on Facebook. But to inspire those who have been pushed into action in new ways in recent weeks, Lewis conceded: “The video had to be played.” Anyone might be upset by seeing such graphic images — and many are — but Resmaa Menakem, a Minneapolis-based racial trauma specialist, says, for many Black people, that pain is amplified.  “When something like this happens, it is not just the grief of watching that brother be destroyed, it is the 400 years of grief that was never addressed,” said Menakem. Aaron Requena periodically takes breaks from Twitter to avoid such images. The 25-year-old photographer in Los Angeles says he’s struggled to balance keeping up with what is happening with not torturing himself at the same time.  “It hits close to home for me because I’ve had interactions with the police where I was just minding my business and had to wonder, ‘Is this going to end for me the way that a lot of these situations end?’” asked Requena, who is Black. “It hits close to home because you know that it could be you next.”  
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The U.S. Supreme Court on Monday handed abortion-rights advocates a victory, striking down a restrictive abortion law in Louisiana that would have left the southern state with only one abortion clinic.The vote was 5-4, with Chief Justice John Roberts siding with the court’s four-member liberal contingent. The decision struck down a law that would have required doctors performing abortions to gain admitting privileges at nearby hospitals, even though abortion-rights activists say patients rarely need to be hospitalized after the procedure.The White House deplored the ruling. Spokeswoman Kayleigh McEnany said it “devalued both the health of mothers and lives of unborn children. Instead of valuing fundamental democratic principles, unelected justices have intruded on the sovereign prerogatives of state governments by imposing their own policy preference in favor of abortion to override legitimate abortion safety regulations.”  In their first abortion case rulings, conservative justices Neil Gorsuch and Brett Kavanaugh, President Donald Trump’s appointments, were in the minority, voting to uphold the Louisiana law that would have overturned a 2016 ruling by a different group of court justices that struck down an almost identical restrictive abortion law in Texas.In concurring with the court’s liberal wing, Roberts said respect for court precedent in previous decisions “requires us, absent special circumstances, to treat like cases alike. The Louisiana law imposes a burden on access to abortion just as severe as that imposed by the Texas law, for the same reasons. Therefore, Louisiana’s law cannot stand under our precedents.”Roberts’s alignment with the court’s four liberals was striking because he declared that he continues to believe that the 2016 Texas case was “wrongly decided,” but that it nonetheless should be adhered to in the Louisiana case. The decision was a significant win for U.S. abortion-rights advocates and a setback for abortion foes who had hoped that Gorsuch and Kavanaugh would lead the court to impose more abortion restrictions and eventually overturn the landmark 1973 Roe v. Wade decision guaranteeing abortion rights in the U.S.Abortion-rights advocates contended that the Louisiana law was a veiled attempt to chip away at the legality of abortion in the U.S. Justice Stephen Breyer wrote that the majority “consequently hold that the Louisiana statute is unconstitutional.” He said the evidence in the Louisiana dispute “also shows that opposition to abortion played a significant role in some hospitals’ decisions to deny admitting privileges” to abortion practitioners.Health experts estimate that more than 800,000 abortions a year are performed in the U.S., although the figure is down substantially from the 1978 to 1997 period when the annual figures topped a million abortions and peaked at more than 1.4 million.The question before the court in Monday’s ruling was whether Louisiana’s 2014 law requiring doctors at abortion clinics to have admitting privileges at nearby hospitals would unduly burden women seeking an abortion.Abortion practitioners have said it had been all but impossible for a variety of reasons for them to obtain hospital admitting privileges, which would have left Louisiana with a single abortion clinic, in the state’s biggest city, New Orleans.However, the law’s supporters said it would protect the health and safety of women seeking abortions and would help ensure the competence of doctors.But abortion-rights supporters cited the rarity of the need for hospitalization after an abortion and said women could, if needed, be hospitalized whether their abortion practitioner had admitting privileges or not.The Texas law struck down in 2016 said the admitting privilege provision did not have a medical benefit.In that decision, now-retired justice Anthony Kennedy joined the court’s four liberals to form a majority. At that time before Trump assumed the presidency, the Department of Justice argued that the Texas law should be struck down. But under Trump, the department backed the Louisiana law.The court’s 2016 decision said the admitting-privileges requirement “provides few, if any, health benefits for women, poses a substantial obstacle to women seeking abortions, and constitutes an ‘undue burden’ on their constitutional right to do so.”
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