Decades’ worth of man-made junk is cluttering up Earth’s orbit, posing a threat to spaceflight and the satellites we rely on for weather reports, air travel and global communications.

More than 750,000 fragments larger than a centimeter are already thought to orbit Earth, and each one could badly damage or even destroy a satellite.

Last year, a tiny piece of debris punched a gaping hole in the solar panel of Copernicus Sentinel-1A, an observation satellite operated by the European Space Agency, or ESA. A solar array brought back from the Hubble Telescope in 1993 showed hundreds of tiny holes caused by dust-sized debris.

Experts meeting in Germany this week said the problem could get worse as private companies such as SpaceX, Google and Arlington, Virginia-based OneWeb send a flurry of new satellites into space over the coming years. They said steps should be taken to reduce space debris.

Getting all national space agencies and private companies to comply with international guidelines designed to prevent further junk in orbit would be a first step. At the moment those rules — which can be costly to implement — aren’t legally binding.

ESA’s director-general, Jan Woerner, told The Associated Press on Friday that so-called mega-constellations planned by private companies should have a maximum orbital lifetime of 25 years. After that, the satellite constellations would need to move out of the way, either by going into a so-called `graveyard orbit’ or returning to Earth.

That’s because dead satellites pose a double danger: they can collide with other spacecraft or be hit by debris themselves, potentially breaking up into tiny pieces that become a hazard in their own right.

The nightmare scenario would be an ever-growing cascade of collisions resulting in what’s called a Kessler syndrome — named after the NASA scientist who first warned about it four decades ago — that could render near-Earth orbits unusable to future generations.

“Without satellites, you don’t have weather reports, live broadcasts from the other side of the planet, stock market, air travel, online shopping, sat-nav in your car,” Rolf Densing, ESA’s director of operations, said. “You might as well move into a museum if all the satellites are switched off.”

Even if future launches adhere to the guidelines, though, there’s the question of what to do with all of the debris already in orbit.

“We have to clean the vacuum, which means we need a vacuum cleaner,” Woerner said.

Just how such a device would work is still unclear. Proposals include garbage-cleaning spacecraft armed with harpoons, nets, robotic arms and even lasers to fry really small bits of debris.

Luisa Innocenti, the head of ESA’s “clean space” initiative, said a mission is already in the works to bring down a very large piece of debris.

“It’s a very complex operation because nobody wants to fail,” she said. “Nobody wants to hit the debris and create another cloud of debris.”
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The United Nations’ World Health Organization says millions of lives could be saved if people infected with viral hepatitis were tested and treated for these potentially fatal diseases.

New WHO data from the just released Hepatitis 2017 report show an estimated 325 million people globally are living with chronic hepatitis B or hepatitis C virus infections.

WHO said hundreds of thousands of people infected with these diseases are dying because they lack access to life-saving testing and treatment. The agency noted that most people are untested and do not even know that they are infected.

Consequently, WHO said they remain untreated and are at risk of “a slow progression to chronic liver disease, cancer and death.”

Hepatitis B virus is transmitted between people through contact with blood or other body fluids. Hepatitis C virus is spread through direct contact with infected blood.

Latest estimates show that viral hepatitis caused 1.34 million deaths in 2015 and that some 1.75 million people were newly infected with hepatitis C, bringing the total number of people living with this disease globally to 71 million.

Comparable to TB

Gottfried Hirnschall, director of WHOs department of HIV/global hepatitis program, said that the number of deaths from viral hepatitis was comparable to that of tuberculosis.

However, he noted that hepatitis kills more people than HIV, the virus that causes AIDS, and significantly more than malaria.

“What is, however, the difference between hepatitis and those three other diseases is that the trend for hepatitis is upwards. We are seeing an increase in mortality while for the other three diseases, it has been going down over the years,” Hirnschall said. “Since 2000 and 2015, we have seen a 22 percent increase from one million, as I said, to 1.34 million.”

Hirnschall said there was a range of interventions and tools, including highly effective vaccines and medicines that can prevent hepatitis from becoming a chronic and fatal disease.

WHO estimates 257 million people worldwide were living with chronic hepatitis B in 2015. However, it noted that new infections have been falling dramatically thanks to increased coverage of HBV vaccination among children.

Hepatitis B is mainly transmitted in the first years of life from mother to child and is most prevalent in the Western Pacific and African regions.

While this safe and effective vaccine has been around since 1982, nations have been slow to use it. But Ana Maria Henao Restrepo, team leader of the department of immunization, vaccines and biologicals, observed that this has changed.

She said 95 percent or 185 countries now use the hepatitis B vaccine in routine immunization programs.

“That is great and as I mentioned because of this, 85 percent of the infants worldwide are protected with three doses of hepatitis B vaccine. Where we are lagging behind is on the first dose that is given after birth. It is very important to prevent infections from the mother,” she said.

Restrepo said only 50 percent of countries were delivering this vaccine. Without this vaccine, she said “people become chronically infected and require medication and diagnosis” throughout their lifetime.

Unsafe injections

Unsafe injections in health care settings and injecting drug use are the most common modes of hepatitis C transmission. The problem is most widespread in the Eastern Mediterranean and European regions.

While using clean needles and syringes will prevent transmission of the disease, Gottfried Hirnschall said there is a highly effective drug that can cure hepatitis C within a relatively short time.

“A person needs to take a single tablet or a tablet every day for two to three months and most of the people will be cured.”

He said few people have availed themselves of this treatment for a long time because of the exorbitantly high $84,000 price tag.

“They were very high to start with. They are still very high in many countries, particularly in high-income countries,” he said.

“But, as the report also points out, the price of these treatments has come down considerably. It costs as little as $200 in some countries now, per cure for treatments, which is quite striking.”

Charles Gore, President of the World Hepatitis Alliance said WHO’s Global Hepatitis Report provides an understanding of the true impact of the disease, providing “new data and a set of very specific, global and regional targets to reach by 2030.

“For instance, global deaths from hepatitis must be brought down from 1.34 million to lower than 469,000 people per year,” he said.

Hirnschall said the new possibilities of cure for hepatitis C and the possible elimination of hepatitis B through vaccination have created some positive momentum and greater public attention on these heretofore “silent epidemics.”

“The momentum has clearly been driven by the excitement around some new opportunities we do now have,” he said.
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Catch a wave, and you’re sitting on top of the world. You’re also sitting on top of a unique biome. What does that do to our bodies? One surfer, who is also a chemistry graduate student, is trying to find out what all this wave time is doing to surfers’ bodies. This report by Kevin Enochs is narrated by Robert Raffaele.
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An award-winning documentary has captured the innovative ways farmers and others are trying to make the planet a greener, more sustainable place.

Winner of the 2016 César for best documentary, the French equivalent of an Oscar, Tomorrow charts a road trip in which co-directors Cyril Dion and Mélanie Laurent roam the globe in search of solutions to environmental problems.

Their journey takes them to Icelandic volcanoes, Indian slums and French farmlands, among other places, to tell the stories of ordinary people fighting climate change.

The decision to steer away from doomsday narratives — most recently seen in Leonardo DiCaprio’s “Before the Flood” — came from the realization that such an approach failed to spur people into action, Dion said.

“When we focus on catastrophe, and on things that raise fear, it triggers mechanisms in the brain of rejection, flight and fear,” the longtime environmental activist said in a phone interview ahead of the film’s U.S. release Friday.

The film begins in the United States, where two California professors discuss their milestone 2012 study concluding climate change may signal a new cycle of mass extinction.

Soon afterward, Dion and Laurent — a French actress known for her role in “Inglourious Basterds” — hit the road.

Public plantings

In Britain, they visit the market town of Todmorden where residents have seized public spaces to plant fruit, vegetables and herbs — which pedestrians are encouraged to pick.

In the French city of Lille, the CEO of an envelope company shows them how bamboo is grown in the factory’s wastewater to feed a wood boiler that powers the unit’s central heating.

And in Copenhagen, local planners explain how building a labyrinth of bike paths is part of efforts to become first carbon-free capital by 2025.

“We don’t make the cities to make the cars happy, to make the modernistic planners and architects happy,” Jan Gehl, a local architect and urban planner, says in the film. “We have to make the cities so that citizens can have a good life and a good time.”

Dion said he was confident the film would appeal to American viewers despite the many U.S. lawmakers who are skeptical about climate change and oppose regulation to combat it.

Since being sworn in January, President Donald Trump has taken several steps to undo climate change regulations put in place by the previous administration.

Trump also promised during his election campaign to pull the United States out of the global climate change pact reached in Paris in 2015.
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They are homely, buck-toothed, pink, nearly hairless and just plain weird, but one of the many odd traits of rodents called naked mole-rats that live in subterranean bliss in the deserts of East Africa could someday be of great benefit to people.

Scientists said on Thursday the rodents, when deprived of oxygen in their crowded underground burrows, survive by switching to a unique type of metabolism based on the sugar fructose rather than the usual glucose, the only animal known to do so.

Metabolizing fructose is a plant strategy, and the researchers were surprised to see it in a mammal. They now hope to harness lessons learned from this rodent to design future therapies for people to prevent calamitous damage during heart attacks or strokes when oxygenated blood cannot reach the brain.

Naked mole-rats, they found, can survive up to 18 minutes with no oxygen and at least five hours in low-oxygen conditions that would kill a person in minutes.

More closely related to porcupines than moles or rats, they thrive in colonies boasting up to 300 members including a breeding queen in an insect-like social structure of cooperation in food-gathering and tunnel-digging.

With all those rodents breathing and clogging up burrows, they often encounter low-oxygen and high-carbon dioxide conditions.

“Naked mole-rats have evolved in an extremely different environment from most other mammals and they have had millions of years to figure out how to survive dramatic oxygen deprivation,” said neurobiologist Thomas Park of the University of Illinois at Chicago, who helped lead the study published in the journal Science.

In low-oxygen conditions, they enter a coma-like state and release fructose into the blood. By shifting their metabolism from the normal glucose-based system that relies on oxygen to a fructose-based system that does not, they can fuel vital organs such as the heart and brain.

Naked mole-rats live up to 30 years, decades longer than other rodents, are nearly immune to cancer and do not feel many types of pain. As the only cold-blooded mammal, they huddle together in mole-rat piles in order to keep warm. Their lips close behind their teeth so that they can dig with their teeth without getting dirt in their mouths. Their ears and eyes are tiny, and they have poor eyesight.

“Fructose has been linked to obesity and metabolic syndrome but that’s because we over-consume it in sweet beverages and junk food. Perhaps there is a use, and an important one, for fructose in moderate doses after all,” added molecular biologist Jane Reznick of the Max Delbrück Center for Molecular Medicine in the Helmholtz Association in Berlin.
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Scientists have discovered that compounds derived from some bacteria can lower blood sugar levels in obese people with prediabetes, possibly preventing diabetes itself from developing.

Scientists call the bacteria-derived compounds postbiotics. They are not like probiotics, which are whole, live bacteria people take to change the microbial environment of the gut to ward off disease and improve digestion.  

Postbiotics instead are beneficial pieces of bacteria cell walls that are easily absorbed by the body, which seem to make insulin work better. Postbiotics can also be derived from disease-causing microbes, say researchers.

Role of insulin

Insulin is a hormone produced by the pancreas that ferries glucose from food into cells to nourish the body.  

In people with prediabetes, insulin becomes less effective at its job.

Postbiotics seem to boost the hormone’s effectiveness.  At least that’s what researchers at McMaster University in Canada’s Ontario province saw in experiments with obese mice.  

Obesity is a risk factor for prediabetes, also known as metabolic syndrome. Other risk factors for metabolic syndrome include high blood pressure and elevated cholesterol.

Researchers say their work is designed to help obese individuals with prediabetes.  

Biomedical sciences professor Jonathan Schertzer is senior author of a paper on postbiotics published in the journal Cell Metabolism.

To the extent that postbiotics are byproducts of bacteria in the gut, Schertzer says it’s just a matter of unleashing their beneficial effects.

“The bacteria in our guts are constantly dying and being turned over, and they’re producing a lot of this compound, this post-biotic,” Schertzer said. “So now we want to see if it’s a viable approach to increase that in obese people, or allow it to get through the gut, because the gut is a significant barrier.  It’s supposed to keep all of these things out.

“But there are good things that the gut is keeping out as well. … We want to see if we can manipulate that and get some of the good things to get through,” he added.

Reducing the risk

Reducing inflammation to lessen the risk of diabetes and other diseases is an active area of research.

Schertzer says that’s why there’s interest in postbiotics and some other anti-inflammatory compounds contained in the pain reliever aspirin.

There also is an existing drug to treat a cancer called osteosarcoma, he says, that seems to work on the same biological pathways as postbiotics.  

McMaster researchers are interested in seeing if that drug also reduces blood glucose levels in obese animals.

Schertzer says investigators are poised to begin human clinical trials of postbiotics,as a way to head off diabetes in obese individuals headed in that direction.
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Marijuana enthusiasts in the United States celebrate April 20 — or 4/20 — as an informal holiday, but this year they have something else to get excited about: New polling data show support for legalization of the drug is at an all-time high.

Sixty percent of Americans say they support the legalization of marijuana, according to a poll released Thursday by Quinnipiac University. The same poll taken in December 2012 showed 51 percent of respondents supported legalization.

“From a stigmatized, dangerous drug bought in the shadows, to an accepted treatment for various ills, to a widely accepted recreational outlet, marijuana has made it to the mainstream,” Tim Malloy, assistant director of the Quinnipiac University Poll, said in a statement.

According to the poll, an overwhelming 94 percent of respondents said they support the use of marijuana by adults for medicinal purposes — also the highest level of support seen in the poll’s history.

Seventy-three percent of Americans said they oppose enforcement of federal laws against marijuana in states that have legalized medical or recreational marijuana.

Currently, 29 states have legalized marijuana use for medicinal purposes, and eight states and the District of Columbia have legalized recreational use.

Marijuana advocates across the country held events to observe the annual 4/20 quasi-holiday. In Washington, D.C., activists planned to distribute free joints to congressional staffers on Capitol Hill. However, Capitol Police interrupted the event, arresting two women and one man, and charging them with possession with intent to distribute pot. Four other women were charged with simple possession.

One of the organizers, Nikolas Schiller, told the Associated Press that police “decided to play politics” with the demonstration and that the people arrested committed no crimes. “We’ll see them in court,” Schiller said.
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Dow Chemical is pushing the Trump administration to scrap the findings of federal scientists who point to a family of widely used pesticides as harmful to about 1,800 critically threatened or endangered species.

Lawyers representing Dow, whose CEO also heads a White House manufacturing working group, and two other makers of organophosphates sent letters last week to the heads of three Cabinet agencies. The companies asked them “to set aside” the results of government studies the companies contend are fundamentally flawed.

The letters, dated April 13, were obtained by The Associated Press.

Dow Chemical chairman and CEO Andrew Liveris is a close adviser to President Donald Trump. The company wrote a $1 million check to help underwrite Trump’s inaugural festivities.

Pesticide study

Over the last four years, government scientists have compiled an official record running more than 10,000 pages showing the three pesticides under review — chlorpyrifos, diazinon and malathion — pose a risk to nearly every endangered species they studied. Regulators at the three federal agencies, which share responsibilities for enforcing the Endangered Species Act, are close to issuing findings expected to result in new limits on how and where the highly toxic pesticides can be used.

The industry’s request comes after EPA Administrator Scott Pruitt announced last month he was reversing an Obama-era effort to bar the use of Dow’s chlorpyrifos pesticide on food after recent peer-reviewed studies found that even tiny levels of exposure could hinder the development of children’s brains. In his prior job as Oklahoma’s attorney general, Pruitt often aligned himself in legal disputes with the interests of executives and corporations who supported his state campaigns. He filed more than one dozen lawsuits seeking to overturn some of the same regulations he is now charged with enforcing.

‘Restore regulatory sanity’

Pruitt declined to answer questions from reporters Wednesday as he toured a polluted Superfund site in Indiana. A spokesman for the agency later told AP that Pruitt won’t “prejudge” any potential rule-making decisions as “we are trying to restore regulatory sanity to EPA’s work.”

“We have had no meetings with Dow on this topic, and we are reviewing petitions as they come in, giving careful consideration to sound science and good policymaking,” said J.P. Freire, EPA’s associate administrator for public affairs. “The administrator is committed to listening to stakeholders affected by EPA’s regulations, while also reviewing past decisions.”

The office of Commerce Secretary Wilbur Ross, who oversees the Natural Marine Fisheries Service, did not respond to emailed questions. A spokeswoman for Interior Secretary Ryan Zinke, who oversees the Fish and Wildlife Service, referred questions back to EPA.

Dow’s rebuttal

As with the recent human studies of chlorpyrifos, Dow hired its own scientists to produce a lengthy rebuttal to the government studies showing the risks posed to endangered species by organophosphates.

The EPA’s recent biological evaluation of chlorpyrifos found the pesticide is “likely to adversely affect” 1,778 of the 1,835 animals and plants accessed as part of its study, including critically endangered or threatened species of frogs, fish, birds and mammals. Similar results were shown for malathion and diazinon.

In a statement, the Dow subsidiary that sells chlorpyrifos said its lawyers asked for the EPA’s biological assessment to be withdrawn because its “scientific basis was not reliable.”

“Dow AgroSciences is committed to the production and marketing of products that will help American farmers feed the world, and do so with full respect for human health and the environment, including endangered and threatened species,” the statement said. “These letters, and the detailed scientific analyses that support them, demonstrate that commitment.”

FMC Corp., which sells malathion, said the withdrawal of the EPA studies will allow the necessary time for the “best available” scientific data to be compiled.

“Malathion is a critical tool in protecting agriculture from damaging pests,” the company said.

Diazinon maker Makhteshim Agan of North America Inc., which does business under the name Adama, did not respond to emails seeking comment.

Acceptable methods

Environmental advocates were not surprised the companies might seek to forestall new regulations that might hurt their profits, but said Wednesday that criticism of the government’s scientists was unfounded. The methods used to conduct EPA’s biological evaluations were developed by the National Academy of Sciences.

Brett Hartl, government affairs director for the Center for Biological Diversity, said Dow’s experts were trying to hold EPA scientists to an unrealistic standard of data collection that could only be achieved under “perfect laboratory conditions.”

“You can’t just take an endangered fish out of the wild, take it to the lab and then expose it to enough pesticides until it dies to get that sort of data,” Hartl said. “It’s wrong morally, and it’s illegal.”

Derived from nerve gas

Originally derived from a nerve gas developed by Nazi Germany, chlorpyrifos has been sprayed on citrus fruits, apples, cherries and other crops for decades. It is among the most widely used agricultural pesticides in the United States, with Dow selling about 5 million pounds domestically each year.

As a result, traces of the chemical are commonly found in sources of drinking water. A 2012 study at the University of California at Berkeley found that 87 percent of umbilical-cord blood samples tested from newborn babies contained detectable levels of chlorpyrifos.

In 2005, the Bush administration ordered an end to residential use of diazinon to kill yard pests such as ants and grub worms after determining that it poses a human health risk, particularly to children. However it is still approved for use by farmers, who spray it on fruits and vegetables.

Malathion is widely sprayed to control mosquitoes and fruit flies. It is also an active ingredient in some shampoos prescribed to children for treating lice.

A coalition of environmental groups has fought in court for years to spur EPA to more closely examine the risk posed to humans and endangered species by pesticides, especially organophosphates.

“Endangered species are the canary in the coal mine,” Hartl said. Since many of the threatened species are aquatic, he said they are often the first to show the effects of long-term chemical contamination in rivers and lakes used as sources of drinking water by humans.

Dow, which spent more than $13.6 million on lobbying in 2016, has long wielded substantial political power in the nation’s capital. There is no indication the chemical giant’s influence has waned.

When Trump signed an executive order in February mandating the creation of task forces at federal agencies to roll back government regulations, Dow’s chief executive was at Trump’s side.

“Andrew, I would like to thank you for initially getting the group together and for the fantastic job you’ve done,” Trump said as he signed the order during an Oval Office ceremony. The president then handed his pen to Liveris to keep as a souvenir.

Rachelle Schikorra, the director of public affairs for Dow Chemical, said any suggestion that the company’s $1 million donation to Trump’s inaugural committee was intended to help influence regulatory decisions made by the new administration is “completely off the mark.”

“Dow actively participates in policymaking and political processes, including political contributions to candidates, parties and causes, in compliance with all applicable federal and state laws,” Schikorra said. “Dow maintains and is committed to the highest standard of ethical conduct in all such activity.”
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